Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers.
نویسندگان
چکیده
منابع مشابه
automatic verification of authentication protocols using genetic programming
implicit and unobserved errors and vulnerabilities issues usually arise in cryptographic protocols and especially in authentication protocols. this may enable an attacker to make serious damages to the desired system, such as having the access to or changing secret documents, interfering in bank transactions, having access to users’ accounts, or may be having the control all over the syste...
15 صفحه اولEfficient gene transfer into various mammalian cells, including non-hepatic cells, by baculovirus vectors.
A baculovirus (Autographa californica nucleopolyhedrovirus) vector containing a strong promoter, the CAG promoter, was developed to introduce foreign genes into mammalian cells. Recombinant baculoviruses carrying a reporter gene under the control of the CAG promoter were inoculated into various mammalian cell lines. High-level expression was observed not only in hepatocytes but also in other no...
متن کاملStructural studies of biologically active glycosylated polyamidoamine (PAMAM) dendrimers.
The partial modification of carboxylic acid terminated polyamidoamine (PAMAM) dendrimers with glucosamine has been reported to give dendrimer glucosamine conjugates novel immuno-modulatory and anti-angiogenic properties. Experimental analysis of these glycosylated dendrimers showed that, on average, eight glucosamine molecules were covalently bound to each dendrimer. In order to better understa...
متن کاملInteraction between polyamidoamine (PAMAM) dendrimers and bovine insulin.
OBJECTIVE In this study the mechanism of interactions between polyamidoamine (PAMAM) dendrimers and bovine insulin was examined. The insulin is a 51 amino acid peptide-hormone involved in the homeostasis of blood glucose levels. This molecule consists of two chains - A and B - linked by two disulphide bridges. As insulin contains four tyrosine residues it was possible to evaluate dendrimers eff...
متن کاملSilica scale inhibition by polyaminoamide STARBURST® dendrimers
This paper reports the inhibition efficiency of a family of polyaminoamide (PAMAM) STARBURST® dendrimers in colloidal SiO2 growth. PAMAMs of various generations (0.5, 1.5, 2.5 with –COOH termini, and 1, and 2 with –NH2 termini) were tested and compared to control samples. Superiority of the dendrimer inhibitors with –NH2 termini (maintaining∼380 ppm soluble SiO2 after 12 h) versus those with –C...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1996
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.93.10.4897